Synthesis of aspirin abstract: the purpose of this lab is to synthesise acetylsalicylic acid (aspirin) by creating a reaction between acetic anhydride and salicylic. Synopsis the objective of this experiment is to enable us to conduct the synthesis of aspirin, reinforce the skills of recrystallisation and. Reminder: these notes are meant to supplement, not replace, the laboratory manual synthesis of aspirin notes history and application aspirin is one of the most. An experiment is described that is suitable for the early portion of the laboratory in a general chemistry course and integrates organic examples it is the two-step. 1 aspirin is the common name for the compound acetylsalicylic acid, widely used as a fever reducer and as a pain killer salicylic acid, whose name comes from salix.
Page 1 of 5 experiment: synthesis of aspirin background “aspirin, which ranks as the most widely used drug in the united states, is one of a series of. Aspirin is the prototypical analgesic used in the treatment of mild to moderate pain it has anti-inflammatory and antipyretic properties and acts as an inhibitor of. Aspirin synthesis lab by abigail arrigo, alexis arrigo, christian bruns, alissa lockwood, and justin rose objective 1 the first objective of this lab was to.
Aspirin (2nd edition) compiled by david lewis edited by colin osborne and maria pack designed by imogen bertin and sara roberts first published by the royal society. The chemical equation for the synthesis of aspirin is c7h6o3 + c4h6o3 – c9h8o4 +c2h4o2, which is a reaction of salicylic acid with acetic anhydride in the presence. Esterification reaction: the synthesis and purification of 2-acetoxybenzoic acid and subsequent analysis of the pure synthesis of aspirin data. How to make aspirin - acetylsalicylic acid first, gather the chemicals and equipment used to synthesize the aspirin: aspirin synthesis materials 30 g salicylic. Synthesis and analysis of aspirin 3 add 50 ml of acetic anhydride and 5 drops of 85% phosphoric acid swirl the mixture if necessary, use a sparingly small amount.
83 experiment 5: synthesis of aspirin salicylic acid has the same analgesic properties as aspirin and was used for many years as a headache medicine. Aspirin has had a long history aspirin: turn-of-the-century miracle drug ultimately leading vane to consider that aspirin was inhibiting the synthesis of. Decompose residual acetic anhydride if an oil appears instead of a solid, reheat the flask in the hot water bath until the oil disappears and again cool. A student researched lab analysis about the synthesis and characterization of aspirin by measuring the melting point as well as taking a uv spectroscopy. Part of ncssm core collection: this video shows the synthesis of aspirin http://wwwdltncssmedu.
The history of aspirin (also known as acetylsalicylic acid or asa) in the course of his work on the synthesis and properties of various acid anhydrides. The synthesis and analysis of aspirin mariam el-magbri department of chemistry, american university, washington, dc 20016 date of publication: february 26, 2014. I introduction organic synthesis is the process where a desired organic compound is constructed or prepared from commercially available materials.
Carbon introduction aspirin is a pain relieving compound that most students will be familiar with, thus its synthesis gives students an insight into how chemistry. Chem 322: esterification reaction synthesis of aspirin introduction aspirin is one of the milder and least expensive pain relievers available. Aspirin has been used as a medicine by the ancient greeks and the pharaohs of egypt it is effective in reducing pain (it is an analgesic), reducing inflammation. Chan 2 experimental synthesis of aspirin in the first part of the experiment, aspirin was synthesized a filter crucible and mortar and pestle were.